An 11-year-old boy and his 7-year-old sister live in a suburban house with their human parents, bickering and feuding like all other siblings. But there's a twist: the brother is a 4-pound chicken and the sister is a 400-pound cow!
In "Can Cow Come Out And Play?" Red plots to make Cow play with him by locking the rest of the world into a trailer. Then, Cow attempts to enlarge her horns to impress a boy at school in "Horn Envy."
Chicken learns to "Be Careful What You Wish For" when Cow's incessant chattering makes him wish that Cow would never talk to him again. Then, Flem and Earl believe they're "Lost At Sea," but they're actually floating in a steamy bathtub.
Tired of being manhandled all the time, "Cow's Toys" depart to find their original owner. Next, Cow and Chicken want to get an ice cream from the truck driven by Red, but he's the "I Scream Man," not the "ice cream man."
Dad brings home a pet jackal for Cow and Chicken in "The Night of the Ed." Later, Chicken discovers he enjoys "Cow's Pies." Then, in "I.R. Good Dog," an obnoxious child purchases Weasel and Baboon as pets.
Red masquerades as a famous blues singer in "Cow And Chicken Blues." Then, in "The Ballad of Cow and Chicken," teacher sings a ballad about Red's body crabs. Later, Red devises a scam to burn and rebuild house in "I.R. Good Salesman."
COW AND CHICKEN BLUES/THE BALLARD OF COW AND CHICKEN/I.R. GOOD SALESMAN
First, in "Chachi, The Chewing-Gum Seal," Cow creates a seal out of chewing gum, wishes for it to come to life, and it does. Next, the "Black Sheep of the Family" arrives for a visit with Cow and Chicken.
CHACHI, THE CHEWING-GUM SEAL/BLACK SHEEP OF THE FAMILY/ENEMY CAMP
When Red sells Cow a magic potion, Cow thinks that she's now an "Invisible Cow." Later, Cow makes friends with the "Monster in the Closet." Finally, in "I Am Hairstylist," Baboon takes over Weasel's salon while he's away and performs atrocious haircuts.
INVISIBLE COW/MONSTER IN THE CLOSET/I AM HAIRSTYLIST
Cow and Chicken discover "Cow's Horse" in their yard. Then Red becomes "Red Butler" at Cow and Chicken's house. Later, in "Baboon's Paw," a strange old man offers Baboon a monkey's paw capable of granting its owner wishes.